KandelLab

Principles of Neural Science, in Simulation

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§1 Nernst Equation — Ion Equilibrium Potential

E = (RT / zF) · ln([X]out / [X]in)

The Nernst equation describes the equilibrium potential of a single ion across the membrane. When the membrane is permeable only to that ion, the membrane potential equals its equilibrium potential. Raising the temperature or increasing the concentration gradient increases the absolute value of the equilibrium potential.

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Parameters

°C

Equilibrium Potentials by Ion

IonValence z[X]₀ (mM)[X]ᵢ (mM)E (mV)
K⁺1.00005.0000140.0000-89.0540
Na⁺1.0000145.000015.000060.6312
Ca²⁺2.00002.00000.0001132.3367
Cl⁻-1.0000110.000010.0000-64.0844