KandelLab

Principles of Neural Science, in Simulation

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§5 Synapse Model — EPSP/IPSP and Spatiotemporal Integration

ΔV(t) = w · (t-ts)/τ · exp(1 - (t-ts)/τ) · Θ(t-ts)

Synaptic events are described by an alpha function: a fast rise followed by a slow decay. Multiple synaptic inputs can summate in time (high-frequency pulses) or in space (many synapses active at once), driving the membrane potential to threshold.

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Parameters

ms
mV
ms